Medicine items are essential for surviving tough battles, exploring Lumiose City, and keeping your team prepared for Alpha Pokémon encounters, Rogue Mega Pokémon, and long mission routes. This fully expanded guide explains every type of medicine, what each item does, when to use it, and where to find it throughout the game.

 

 

What Medicine Items Do

Medicine items play several important roles in Pokémon Legends: Z-A:

• Restore HP during or after battle
• Revive fainted Pokémon
• Cure status conditions such as poison or paralysis
• Restore Power Points (move usage)
• Offer cheaper healing options via drink stands or herbal blends

Understanding each item helps you save time, avoid unnecessary fainting, and battle more efficiently.

 

If you're also working on boosting stats, don't forget to check out our Training Items Guide for Power items, Vitamins, and more.

 

1. HP Recovery Items (Healing Medicine)

Healing items restore lost HP. Some are cheap and useful in early areas, while others provide full restoration for late-game battles.

Item	Effect	Best Use	Buy Price
Potion	Heals 20 HP	Early-game, minor chip damage	₽150
Super Potion	Heals 60 HP	Mid-game exploration, regular fights	₽400
Hyper Potion	Heals 120 HP	Strong trainers, high-attack Pokémon	₽600
Max Potion	Fully heals HP	Boss fights, emergency healing	₽1200
Full Restore	Fully heals HP AND removes all status conditions	Best late-game healing item	₽1500
Fresh Water	Heals 30 HP	Cheap, good early alternative	₽200
Soda Pop	Heals 50 HP	Value healing for mid-level teams	₽300
Lemonade	Heals 70 HP	Excellent price-to-heal value	₽400
Moomoo Milk	Heals 100 HP	Great for consistent healing runs	₽600

 

2. Revival Items

Revival Items are used to bring a fainted Pokémon back into battle, restoring its HP so it can keep fighting.

Item	Description	Effect	Price
Revive	Leaf-shaped crystal for fallen Pokémon.	Revives a fainted Pokémon with 50% HP	₽800
Max Revive	Premium revival item.	Revives to full HP	– (usually not purchasable)

 

3. Status-Healing Items

Status-Healing Items cure conditions like paralysis, sleep, burn, poison, and freeze, allowing your Pokémon to recover and keep battling normally.

Item	Description	Effect	Price
Antidote	Basic anti-poison spray.	Cures Poison	₽100
Paralyze Heal	Shock-relief medicine.	Cures Paralysis	₽100
Burn Heal	Burn-relief spray.	Cures Burn	₽100
Ice Heal	Defrosting medicine.	Cures Freeze	₽100
Awakening	Scented spray to wake drowsy Pokémon.	Cures Sleep	₽100
Full Heal	Broad-spectrum medicine.	Cures any status condition	₽200
Lumiose Galette	Local Lumiose pastry.	Cures any status condition	₽350

 

Where to Get Medicine

1. Pokémon Center Shop

This is your most reliable source for healing items. Stock rotates and expands as you progress through main missions, letting you buy stronger Medicines and even Vitamins later.

 

Tip for players:

Before fighting Alpha Pokémon or Rogue Mega Pokémon, buy enough Potions and status cures—these battles hit much harder than normal encounters.

If you need these items quickly, our ZA Held Items page has them all in one place.

 

2. Exploring Lumiose City

Scattered Poké Balls, sparkling ground spots, and hidden alleys often contain Potions, healing drinks, or status cures. Exploration rewards you with plenty of free medicine—perfect for early-game stocking.

 

3. City Food & Drink Stalls

Lumiose's kiosks and bakeries sell healing drinks and treats:

Lemonade, Soda Pop, Fresh Water → Drink stalls

Lumiose Galette → Bakeries

These are cheap alternatives for mid-game healing.

 

How to Use Medicine

1. Open your Satchel from the main menu.
2. Choose the Medicine category.
3. Pick the item you want to use.
4. Choose the Pokémon in your party that needs healing.

Important: You cannot heal a fainted Pokémon with regular HP items—use a Revive, Max Revive, or visit the Pokémon Center.

 

Tips for Managing Medicine Efficiently

Use Potions/Super Potions only in early game—strong opponents will outscale them quickly.

Keep at least:

1–2 Full Restores for emergencies

3–5 Revives before boss fights

A handful of status cures, especially Antidote and Burn Heal

For long routes or multi-stage missions, Moomoo Milk provides the best value per HP.

Don't waste a Full Restore on a small status—the cheaper status-specific sprays save money.